Water resources are the essential for humanity. Today major challenges concerning water resources include the identification of the spatial and temporal dynamics of water resource availability and how this is impacted by climate change and anthropogenic pressure. Vulnerability and resilience of water resources depends on their geographic context from mountains to plains, across arid to humid climates and the extent of impact by water abstraction. The course spans these general themes and terminates with a special focus on the Greater Geneva Region. This will include the role of water supply from Lake Geneva and its surrounding glaciers, impacts of climate change such as severe glacier retreat, heatwaves and droughts and groundwater lowering. The course ends with perspectives on responsible water management.